In a high-risk isolation situation, which item is donned third in the PPE sequence?

• A. Gown
• B. Mask or respirator
• C. Eye protection
• D. Gloves

Answer: (C)

In high-risk isolation, the PPE donning order is arranged to protect you as you prepare to work with a patient. After you’ve done hand hygiene, you put on the gown first to create a barrier for your body and clothing. Next, you don the mask or respirator to protect your breathing. The third piece you add is eye protection, such as goggles or a face shield, to shield the eyes from droplets or splashes. Gloves come last to cover your hands once the face and body barriers are already in place. Eye protection is positioned third because safeguarding the eyes is crucial and you want that barrier in place before completing the final steps with gloves, reducing the chance of contaminating hands or face during the remainder of the donning process.